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Toward a quantitative theory of intrinsically disordered proteins and their function

A large number of proteins are sufficiently unstable that their full 3D structure cannot be resolved. The origins of this intrinsic disorder are not well understood, but its ubiquitous presence undercuts the principle that a protein's structure determines its function. Here we present a quantit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Jintao, Faeder, James R., Camacho, Carlos J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775701/
https://ncbi.nlm.nih.gov/pubmed/19903882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907710106
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