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Human heat shock protein 27-overexpressing mice are protected against acute kidney injury after hepatic ischemia and reperfusion

Liver ischemia-reperfusion injury (IRI) causes acute kidney injury (AKI) in mice characterized by renal endothelial cell apoptosis, renal tubular necrosis, inflammation, and filamentous (F)-actin disruption. Since heat shock protein 27 (HSP27) protects against apoptosis, necrosis, and stabilizes F-a...

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Detalhes bibliográficos
Main Authors: Park, Sang Won, Chen, Sean W. C., Kim, Mihwa, D'Agati, Vivette D., Lee, H. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775579/
https://ncbi.nlm.nih.gov/pubmed/19656912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00317.2009
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