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Neurokinin 1 Receptors Regulate Morphine-Induced Endocytosis and Desensitization of μ-Opioid Receptors in CNS Neurons

μ-Opioid receptors (MORs) are G-protein-coupled receptors (GPCRs) that mediate the physiological effects of endogenous opioid neuropeptides and opiate drugs such as morphine. MORs are coexpressed with neurokinin 1 receptors (NK1Rs) in several regions of the CNS that control opioid dependence and rew...

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Bibliografiske detaljer
Main Authors: Yu, Y. Joy, Arttamangkul, Seksiri, Evans, Christopher J., Williams, John T., von Zastrow, Mark
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775560/
https://ncbi.nlm.nih.gov/pubmed/19129399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4315-08.2009
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