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Steady-state Coupling of Plasma Membrane Calcium Entry to Extrusion Revealed by Novel L-type Calcium Channel Block

The L-type Ca(2+) channel (Ca(V)1.2) is the main pathway for trans-sarcolemmal (SL) Ca(2+) influx in cardiac myocytes. To maintain Ca(2+) homeostasis, chronic SL Ca(2+)-influx must be matched by chronic SL efflux. In this study we tested the hypothesis that chronic down-regulation of SL Ca(2+)-entry...

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Autors principals: Lester, William C, Schroder, Elizabeth A, Burgess, Don E., Yozwiak, Doug, Andres, Douglas A., Satin, Jonathan
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775503/
https://ncbi.nlm.nih.gov/pubmed/19230140
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