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Tissue specific abundance of regulatory T cells correlates with CD8(+) T cell dysfunction and chronic retrovirus loads
Infection of mice with Friend virus induces the activation of CD4(+) regulatory T cells (Tregs) that suppress virus-specific CD8(+) T cells. This suppression leads to incomplete virus clearance and the establishment of virus persistence. We now show that Treg-mediated suppression of CD8(+) T cells i...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2775420/ https://ncbi.nlm.nih.gov/pubmed/19587016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900350 |
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