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Trans-species polymorphism, HLA-disease associations and the evolution of the MHC
Currently, the paradigm is that major histocompatibility complex (MHC) polymorphism is maintained by balancing selection on the immune genes. However, other evolutionary forces besides selection also play a role in the population genetics of this multigene family. van Oosterhout proposed a new theor...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2775235/ https://ncbi.nlm.nih.gov/pubmed/19907702 |
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