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Trans-species polymorphism, HLA-disease associations and the evolution of the MHC

Currently, the paradigm is that major histocompatibility complex (MHC) polymorphism is maintained by balancing selection on the immune genes. However, other evolutionary forces besides selection also play a role in the population genetics of this multigene family. van Oosterhout proposed a new theor...

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Bibliografische gegevens
Hoofdauteur: van Oosterhout, Cock
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775235/
https://ncbi.nlm.nih.gov/pubmed/19907702
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