A supramolecular basis for CD45 tyrosine phosphatase regulation in sustained T cell activation
Transmembrane protein tyrosine phosphatases, such as CD45, can act as both positive and negative regulators of cellular signaling. CD45 positively modulates T cell receptor (TCR) signaling by constitutively priming p56lck through the dephosphorylation of the C-terminal negative regulatory phosphotyr...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2000
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27752/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10963676/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.18.10138 |
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