Mycolactone Gene Expression Is Controlled by Strong SigA-Like Promoters with Utility in Studies of Mycobacterium ulcerans and Buruli Ulcer

Mycolactone A/B is a lipophilic macrocyclic polyketide that is the primary virulence factor produced by Mycobacterium ulcerans, a human pathogen and the causative agent of Buruli ulcer. In M. ulcerans strain Agy99 the mycolactone polyketide synthase (PKS) locus spans a 120 kb region of a 174 kb mega...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Tobias, Nicholas J., Seemann, Torsten, Pidot, Sacha J., Porter, Jessica L., Marsollier, Laurent, Marion, Estelle, Letournel, Franck, Zakir, Tasnim, Azuolas, Joseph, Wallace, John R., Hong, Hui, Davies, John K., Howden, Benjamin P., Johnson, Paul D. R., Jenkin, Grant A., Stinear, Timothy P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2009
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775157/
https://ncbi.nlm.nih.gov/pubmed/19936295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000553
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