Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis

Haematopoietic stem cell (HSC) homeostasis is tightly controlled by growth factors, signalling molecules and transcription factors. Definitive HSCs derived during embryogenesis in the aorta-gonad-mesonephros region subsequently colonize fetal and adult haematopoietic organs1,2. To identify new modul...

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Bibliografiska uppgifter
Huvudupphovsmän: North, Trista E., Goessling, Wolfram, Walkley, Carl R., Lengerke, Claudia, Kopani, Kamden R., Lord, Allegra M., Weber, Gerhard J., Bowman, Teresa V., Jang, Il-Ho, Grosser, Tilo, FitzGerald, Garret A., Daley, George Q., Orkin, Stuart H., Zon, Leonard I.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775137/
https://ncbi.nlm.nih.gov/pubmed/17581586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature05883
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