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Met amplification and tumor progression in Cdkn2a-deficient melanocytes

While many genetic alterations have been identified in melanoma, the relevant molecular events that contribute to disease progression are poorly understood. Most primary human melanomas exhibit loss of expression of the CDKN2A locus in addition to activation of canonical MAPK signaling including RAS...

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Podrobná bibliografie
Hlavní autoři: VanBrocklin, Matthew W., Robinson, James P., Whitwam, Todd, Guilbeault, Adam R., Koeman, Julie, Swiatek, Pamela J., Vande Woude, George F., Khoury, Joseph D., Holmen, Sheri L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2775091/
https://ncbi.nlm.nih.gov/pubmed/19422607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2009.00576.x
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