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Caveolin-1 and Lipid Microdomains Regulate G(s) Trafficking and Attenuate G(s)/Adenylyl Cyclase Signaling

Lipid rafts and caveolae are specialized membrane microdomains implicated in regulating G protein-coupled receptor signaling cascades. Previous studies have suggested that rafts/caveolae may regulate β-adrenergic receptor/Gα(s) signaling, but underlying molecular mechanisms are largely undefined. Us...

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Detalhes bibliográficos
Main Authors: Allen, John A., Yu, Jiang Z., Dave, Rahul H., Bhatnagar, Anushree, Roth, Bryan L., Rasenick, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774991/
https://ncbi.nlm.nih.gov/pubmed/19696145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.060160
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