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A bifunctional Gα(i)/Gα(s) modulatory peptide that attenuates adenylyl cyclase activity
Signaling via G-protein coupled receptors is initiated by receptor-catalyzed nucleotide exchange on Gα subunits normally bound to GDP and Gβγ. Activated Gα·GTP then regulates effectors such as adenylyl cyclase. Except for Gβγ, no known regulators bind the adenylyl cyclase-stimulatory subunit Gα(s) i...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1363735/ https://ncbi.nlm.nih.gov/pubmed/16225870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2005.09.059 |
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