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Control of TCF-4 Expression by VDR and Vitamin D in the Mouse Mammary Gland and Colorectal Cancer Cell Lines

BACKGROUND: The vitamin D receptor (VDR) pathway is important in the prevention and potentially in the treatment of many cancers. One important mechanism of VDR action is related to its interaction with the Wnt/β-catenin pathway. Agonist-bound VDR inhibits the oncogenic Wnt/β-catenin/TCF pathway by...

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Auteurs principaux: Beildeck, Marcy E., Islam, Md, Shah, Salimuddin, Welsh, JoEllen, Byers, Stephen W.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774944/
https://ncbi.nlm.nih.gov/pubmed/19924301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007872
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