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The IL-6-deficient mouse exhibits impaired lymphocytic responses to a vaccine combining live Leishmania major and CpG oligodeoxynucleotides

We have previously reported that vaccination with CpG oligodeoxynucleotides delivered concomitantly with live Leishmania major (Lm/CpG) eliminates lesions associated with live vaccination in C57BL/6 mice. The absence of lesions is at least in part a result of the CpG DNA-mediated activation of derma...

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Detalhes bibliográficos
Main Authors: Wu, Wenhui, Weigand, Luise, Mendez, Susana
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774832/
https://ncbi.nlm.nih.gov/pubmed/19767842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/W09-017
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