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Cellular Assays for High-Throughput Screening for Modulators of Trk Receptor Tyrosine Kinases

Trk receptor tyrosine kinases are required for signal transduction initiated by neurotrophins leading to cell proliferation, differentiation, survival and death. Alterations in Trk kinase activity have been linked to various diseases. To address the need for cell-based assays for screening and study...

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Detalhes bibliográficos
Main Authors: Wang, Jun, Hancock, Michael K, Dudek, Jeanne M, Bi, Kun
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers Ltd. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774616/
https://ncbi.nlm.nih.gov/pubmed/20161825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1875397300801010027
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