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Adenovirus vector production using low-multiplicity infection of 293 cells

The use of low-multiplicity infection of 293 cells in static culture with regular medium replacement was investigated for efficient large-scale production of adenovirus vectors for gene therapy applications. An adenovirus vector carrying the enhanced green fluorescent protein gene (Ad EGFP) was used...

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Autori principali: Yamada, Kentaro, Morishita, Naoya, Katsuda, Tomohisa, Kubo, Shuji, Gotoh, Akinobu, Yamaji, Hideki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774567/
https://ncbi.nlm.nih.gov/pubmed/19585249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-009-9208-x
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