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Complexity in Transcription Control at the Activation Domain–Mediator Interface

Transcript elongation by polymerase II paused at the Egr1 promoter is activated by mitogen-activated protein kinase phosphorylation of the ternary complex factor (TCF) ELK1 bound at multiple upstream sites and subsequent phospho-ELK1 interaction with mediator through the MED23 subunit. Consequently,...

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Detalhes bibliográficos
Main Authors: Balamotis, Michael A., Pennella, Mario A., Stevens, Jennitte L., Wasylyk, Bohdan, Belmont, Andrew S., Berk, Arnold J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774526/
https://ncbi.nlm.nih.gov/pubmed/19417216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.1164302
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