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Complexity in Transcription Control at the Activation Domain–Mediator Interface
Transcript elongation by polymerase II paused at the Egr1 promoter is activated by mitogen-activated protein kinase phosphorylation of the ternary complex factor (TCF) ELK1 bound at multiple upstream sites and subsequent phospho-ELK1 interaction with mediator through the MED23 subunit. Consequently,...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774526/ https://ncbi.nlm.nih.gov/pubmed/19417216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.1164302 |
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