Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples

BACKGROUND: Detection of critical cancer gene mutations in clinical tumor specimens may predict patient outcomes and inform treatment options; however, high-throughput mutation profiling remains underdeveloped as a diagnostic approach. We report the implementation of a genotyping and validation algo...

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Hlavní autoři: MacConaill, Laura E., Campbell, Catarina D., Kehoe, Sarah M., Bass, Adam J., Hatton, Charles, Niu, Lili, Davis, Matt, Yao, Keluo, Hanna, Megan, Mondal, Chandrani, Luongo, Lauren, Emery, Caroline M., Baker, Alissa C., Philips, Juliet, Goff, Deborah J., Fiorentino, Michelangelo, Rubin, Mark A., Polyak, Kornelia, Chan, Jennifer, Wang, Yuexiang, Fletcher, Jonathan A., Santagata, Sandro, Corso, Gianni, Roviello, Franco, Shivdasani, Ramesh, Kieran, Mark W., Ligon, Keith L., Stiles, Charles D., Hahn, William C., Meyerson, Matthew L., Garraway, Levi A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2009
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774511/
https://ncbi.nlm.nih.gov/pubmed/19924296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007887
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