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Chk1 phosphorylation during mitosis: A new role for a master regulator

The human DNA damage responses are modulated by both nonessential and essential pathways. The extensively studied ATM kinase and p53 are examples of the former. While loss-of-function mutations in genes that encode ATM and p53 cause marked predispositions to cancer, the loss of these proteins does n...

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Hlavní autoři: Wilsker, Deborah, Bunz, Fred
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774453/
https://ncbi.nlm.nih.gov/pubmed/19282670
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