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Essential function of Chk1 can be uncoupled from DNA damage checkpoint and replication control
Chk1 is widely known as a DNA damage checkpoint signaling protein. Unlike many other checkpoint proteins, Chk1 also plays an essential but poorly defined role in the proliferation of unperturbed cells. Activation of Chk1 after DNA damage is known to require the phosphorylation of several C-terminal...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2634938/ https://ncbi.nlm.nih.gov/pubmed/19091954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806917106 |
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