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Down-regulation of multiple cell survival proteins in head and neck cancer cells by an apoptogenic mutant of adenovirus type 5

Head and neck squamous cell carcinomas (HNSCC) are one of the leading causes of cancer deaths world wide. Up-regulation of the epidermal growth factor receptor (EGFR) and BCL-2 family anti-apoptosis proteins in these cancers is linked to aggressive tumor growth, metastasis and chemoresistance. Infec...

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Autors principals: Vijayalingam, S., Subramanian, T., Ryerse, Jan, Varvares, Mark, Chinnadurai, G.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774264/
https://ncbi.nlm.nih.gov/pubmed/19631957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.06.048
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