Intravitreal delivery of AAV8 retinoschisin results in cell type-specific gene expression and retinal rescue in the Rs1-KO mouse

X-linked juvenile retinoschisis (XLRS) is a neurodevelopmental abnormality caused by retinoschisin gene mutations. XLRS is characterized by splitting through the retinal layers and impaired synaptic transmission of visual signals resulting in impaired acuity and a propensity to retinal detachment. S...

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Detalhes bibliográficos
Main Authors: Park, TK, Wu, Z, Kjellstrom, S, Zeng, Y, Bush, RA, Sieving, PA, Colosi, P
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774250/
https://ncbi.nlm.nih.gov/pubmed/19458650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.61
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