β(3)-Integrin Expression on Tumor Cells Inhibits Tumor Progression, Reduces Metastasis, and Is Associated with a Favorable Prognosis in Patients with Ovarian Cancer

The role of the vitronectin receptor (α(v)β(3)-integrin) as a tumor promoter seems well established, and, consequently, therapies that block this integrin are currently in clinical testing. We undertook the current study to determine whether α(v)β(3)-integrin is an appropriate target in ovarian canc...

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Main Authors: Kaur, Swayamjot, Kenny, Hilary A., Jagadeeswaran, Sujatha, Zillhardt, Marion R., Montag, Anthony G., Kistner, Emily, Yamada, S. Diane, Mitra, Anirban K., Lengyel, Ernst
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2009
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774080/
https://ncbi.nlm.nih.gov/pubmed/19808644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090028
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