Loss of E-Cadherin Promotes Ovarian Cancer Metastasis via α(5)-Integrin, which Is a Therapeutic Target

E-cadherin loss is frequently associated with ovarian cancer metastasis. Given that adhesion to the abdominal peritoneum is the first step in ovarian cancer dissemination, we reasoned that down-regulation of E-cadherin would affect expression of cell matrix adhesion receptors. We show here that inhi...

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Huvudupphovsmän: Sawada, Kenjiro, Mitra, Anirban K., Radjabi, A. Reza, Bhaskar, Vinay, Kistner, Emily O., Tretiakova, Maria, Jagadeeswaran, Sujatha, Montag, Anthony, Becker, Amy, Kenny, Hilary A., Peter, Marcus E., Ramakrishnan, Vanitha, Yamada, S. Diane, Lengyel, Ernst
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665934/
https://ncbi.nlm.nih.gov/pubmed/18381440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5167
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