Loss of E-Cadherin Promotes Ovarian Cancer Metastasis via α(5)-Integrin, which Is a Therapeutic Target

E-cadherin loss is frequently associated with ovarian cancer metastasis. Given that adhesion to the abdominal peritoneum is the first step in ovarian cancer dissemination, we reasoned that down-regulation of E-cadherin would affect expression of cell matrix adhesion receptors. We show here that inhi...

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Auteurs principaux: Sawada, Kenjiro, Mitra, Anirban K., Radjabi, A. Reza, Bhaskar, Vinay, Kistner, Emily O., Tretiakova, Maria, Jagadeeswaran, Sujatha, Montag, Anthony, Becker, Amy, Kenny, Hilary A., Peter, Marcus E., Ramakrishnan, Vanitha, Yamada, S. Diane, Lengyel, Ernst
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665934/
https://ncbi.nlm.nih.gov/pubmed/18381440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-5167
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