Subcellular Localization of the HER4 Intracellular Domain, 4ICD, Identifies Distinct Prognostic Outcomes for Breast Cancer Patients

Conflicting reports of the prognostic value of HER4 in breast cancer may be explained by distinct activities of the HER4 intracellular domain, 4ICD. Here, immunohistochemical 4ICD staining of archival invasive breast cancers (n = 923) was scored separately for nuclear and cytosolic expression, and t...

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Bibliographic Details
Main Authors: Thor, Ann D., Edgerton, Susan M., Jones, Frank E.
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2009
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Short Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774046/
https://ncbi.nlm.nih.gov/pubmed/19808643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090204
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