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Selective oxidation of carbolide C–H bonds by an engineered macrolide P450 mono-oxygenase
Regio- and stereoselective oxidation of an unactivated C–H bond remains a central challenge in organic chemistry. Considerable effort has been devoted to identifying transition metal complexes, biological catalysts, or simplified mimics, but limited success has been achieved. Cytochrome P450 mono-ox...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2774028/ https://ncbi.nlm.nih.gov/pubmed/19833867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907203106 |
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