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Methionine oxidation contributes to bacterial killing by the myeloperoxidase system of neutrophils

Reactive oxygen intermediates generated by neutrophils kill bacteria and are implicated in inflammatory tissue injury, but precise molecular targets are undefined. We demonstrate that neutrophils use myeloperoxidase (MPO) to convert methionine residues of ingested Escherichia coli to methionine sulf...

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Bibliografiset tiedot
Päätekijät: Rosen, Henry, Klebanoff, Seymour J., Wang, Yi, Brot, Nathan, Heinecke, Jay W., Fu, Xiaoyun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2009
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774013/
https://ncbi.nlm.nih.gov/pubmed/19833874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909464106
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