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Methionine oxidation contributes to bacterial killing by the myeloperoxidase system of neutrophils

Reactive oxygen intermediates generated by neutrophils kill bacteria and are implicated in inflammatory tissue injury, but precise molecular targets are undefined. We demonstrate that neutrophils use myeloperoxidase (MPO) to convert methionine residues of ingested Escherichia coli to methionine sulf...

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Bibliografiske detaljer
Main Authors: Rosen, Henry, Klebanoff, Seymour J., Wang, Yi, Brot, Nathan, Heinecke, Jay W., Fu, Xiaoyun
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774013/
https://ncbi.nlm.nih.gov/pubmed/19833874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909464106
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