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Computational design of ligand binding is not a solved problem

Computational design has been very successful in recent years: multiple novel ligand binding proteins as well as enzymes have been reported. We wanted to know in molecular detail how precise the predictions of the interactions of protein and ligands are. Therefore, we performed a structural analysis...

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Autori principali: Schreier, Bettina, Stumpp, Christian, Wiesner, Silke, Höcker, Birte
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773959/
https://ncbi.nlm.nih.gov/pubmed/19833875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907950106
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