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Computational design of ligand binding is not a solved problem

Computational design has been very successful in recent years: multiple novel ligand binding proteins as well as enzymes have been reported. We wanted to know in molecular detail how precise the predictions of the interactions of protein and ligands are. Therefore, we performed a structural analysis...

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Detalhes bibliográficos
Main Authors: Schreier, Bettina, Stumpp, Christian, Wiesner, Silke, Höcker, Birte
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773959/
https://ncbi.nlm.nih.gov/pubmed/19833875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0907950106
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