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Episodic ataxia type 1 mutations differentially affect neuronal excitability and transmitter release

Heterozygous mutations of KCNA1, the gene encoding potassium channel Kv1.1 subunits, cause episodic ataxia type 1 (EA1), which is characterized by paroxysmal cerebellar incoordination and interictal myokymia. Some mutations are also associated with epilepsy. Although Kv1.1-containing potassium chann...

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Bibliografski detalji
Glavni autori: Heeroma, Joost H., Henneberger, Christian, Rajakulendran, Sanjeev, Hanna, Michael G., Schorge, Stephanie, Kullmann, Dimitri M.
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Limited 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773728/
https://ncbi.nlm.nih.gov/pubmed/19779067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.003582
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