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Cellular procoagulant activity dictates clot structure and stability as a function of distance from the cell surface

BACKGROUND: Thrombin concentration modulates fibrin structure and fibrin structure modulates clot stability; however, the impact of localized, cell surface-driven in situ thrombin generation on fibrin structure and stability has not previously been evaluated. METHODS: Human fibroblasts were incubate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Campbell, Robert A., Overmyer, Katherine A., Bagnell, C. Robert, Wolberg, Alisa S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773697/
https://ncbi.nlm.nih.gov/pubmed/18974382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.176008
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