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Cellular procoagulant activity dictates clot structure and stability as a function of distance from the cell surface
BACKGROUND: Thrombin concentration modulates fibrin structure and fibrin structure modulates clot stability; however, the impact of localized, cell surface-driven in situ thrombin generation on fibrin structure and stability has not previously been evaluated. METHODS: Human fibroblasts were incubate...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773697/ https://ncbi.nlm.nih.gov/pubmed/18974382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.176008 |
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