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Vertebrate Limb Development: Moving from Classical Morphogen Gradients to an Integrated 4-Dimensional Patterning System

A wealth of classical embryological manipulation experiments taking mainly advantage of the chicken limb buds identified the apical ectodermal ridge (AER) and the zone of polarizing activity (ZPA) as the respective ectodermal and mesenchymal key signaling centers coordinating proximodistal (PD) and...

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Detalhes bibliográficos
Main Authors: Bénazet, Jean-Denis, Zeller, Rolf
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773624/
https://ncbi.nlm.nih.gov/pubmed/20066096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a001339
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