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Vertebrate Limb Development: Moving from Classical Morphogen Gradients to an Integrated 4-Dimensional Patterning System

A wealth of classical embryological manipulation experiments taking mainly advantage of the chicken limb buds identified the apical ectodermal ridge (AER) and the zone of polarizing activity (ZPA) as the respective ectodermal and mesenchymal key signaling centers coordinating proximodistal (PD) and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bénazet, Jean-Denis, Zeller, Rolf
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773624/
https://ncbi.nlm.nih.gov/pubmed/20066096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a001339
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