Cargando...
MMR/c-Abl-dependent activation of ING2/p73α signaling regulates the cell death response to N-methyl-N’-nitro-N-nitrosoguanidine
Agents inducing O(6)-methylguanine (O(6)MeG) in DNA such as N-methyl-N’-nitro-N-nitrosoguanidine (MNNG) are cytotoxic and a deficiency in mismatch repair (MMR) results in lack of sensitivity to this genotoxin (termed alkylation tolerance). Here, we show that ING2, a member of the inhibitor of growth...
Guardado en:
| Autores principales: | , , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2009
|
| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773549/ https://ncbi.nlm.nih.gov/pubmed/19766113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.09.010 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|