ロード中...

The p53 target Wig-1 regulates p53 mRNA stability through an AU-rich element

The p53 target gene Wig-1 encodes a double-stranded-RNA-binding zinc finger protein. We show here that Wig-1 binds to p53 mRNA and stabilizes it through an AU-rich element (ARE) in the 3′ UTR of the p53 mRNA. This effect is mirrored by enhanced p53 protein levels in both unstressed cells and cells e...

詳細記述

保存先:
書誌詳細
主要な著者: Vilborg, Anna, Glahder, Jacob A., Wilhelm, Margareta T., Bersani, Cinzia, Corcoran, Martin, Mahmoudi, Salah, Rosenstierne, Maiken, Grandér, Dan, Farnebo, Marianne, Norrild, Bodil, Wiman, Klas G.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773521/
https://ncbi.nlm.nih.gov/pubmed/19805223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900862106
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!