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Mcl-1 Functions as Major Epidermal Survival Protein Required for Proper Keratinocyte Differentiation
Rapid down-regulation of the anti-apoptotic Bcl-2 family protein Mcl-1 is required for UV-induced apoptosis, underlining an important role for Mcl-1 in epidermal pathology. To determine if Mcl-1 has a specific role in normal keratinocyte (KC) biology, Mcl-1 was down-regulated in human KCs by RNAi an...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773513/ https://ncbi.nlm.nih.gov/pubmed/19037233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2008.363 |
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