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Cleavage of the SARS Coronavirus Spike Glycoprotein by Airway Proteases Enhances Virus Entry into Human Bronchial Epithelial Cells In Vitro

BACKGROUND: Entry of enveloped viruses into host cells requires the activation of viral envelope glycoproteins through cleavage by either intracellular or extracellular proteases. In order to gain insight into the molecular basis of protease cleavage and its impact on the efficiency of viral entry,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kam, Yiu-Wing, Okumura, Yuushi, Kido, Hiroshi, Ng, Lisa F. P., Bruzzone, Roberto, Altmeyer, Ralf
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773421/
https://ncbi.nlm.nih.gov/pubmed/19924243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007870
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