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Targeted delivery of bleomycin to the brain using photo-chemical internalization of Clostridium perfringens epsilon prototoxin

Cells infiltrating into normal brain from malignant brain tumors are protected by the blood brain barrier (BBB) which prevents the delivery and limits the effects of anti-tumor agents. We have evaluated the ability of photochemical internalization (PCI) to limit the effects of an agent known to broa...

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Autores principales: Hirschberg, Henry, Zhang, Michelle J., Gach, H. Michael, Uzal, Francisco A., Peng, Qian, Sun, Chung-Ho, Chighvinadze, David, Madsen, Steen J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer US 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773371/
https://ncbi.nlm.nih.gov/pubmed/19506813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-009-9930-4
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