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Targeted delivery of bleomycin to the brain using photo-chemical internalization of Clostridium perfringens epsilon prototoxin

Cells infiltrating into normal brain from malignant brain tumors are protected by the blood brain barrier (BBB) which prevents the delivery and limits the effects of anti-tumor agents. We have evaluated the ability of photochemical internalization (PCI) to limit the effects of an agent known to broa...

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Detalhes bibliográficos
Main Authors: Hirschberg, Henry, Zhang, Michelle J., Gach, H. Michael, Uzal, Francisco A., Peng, Qian, Sun, Chung-Ho, Chighvinadze, David, Madsen, Steen J.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773371/
https://ncbi.nlm.nih.gov/pubmed/19506813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-009-9930-4
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