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Interaction of major genes predisposing to hepatocellular carcinoma with genes encoding signal transduction pathways influences tumor phenotype and prognosis

Studies on rodents and humans demonstrate an inherited predisposition to hepatocellular carcinoma (HCC). Analysis of the molecular alterations involved in the acquisition of a phenotype resistant or susceptible to hepatocarcinogenesis showed a deregulation of G1 and S phases in HCC of genetically su...

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Bibliografiske detaljer
Main Authors: Feo, Francesco, Frau, Maddalena, Pascale, Rosa Maria
Format: Artigo
Sprog:Inglês
Udgivet: The WJG Press and Baishideng 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773299/
https://ncbi.nlm.nih.gov/pubmed/19034960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.14.6601
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