GIGYF2 gene disruption in mice results in neurodegeneration and altered insulin-like growth factor signaling

Grb10-Interacting GYF Protein 2 (GIGYF2) was initially identified through its interaction with Grb10, an adapter protein that binds activated IGF-I and insulin receptors. The GIGYF2 gene maps to human chromosome 2q37 within a region linked to familial Parkinson's disease (PARK11 locus), and ass...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Giovannone, Barbara, Tsiaras, William G., de la Monte, Suzanne, Klysik, Jan, Lautier, Corinne, Karashchuk, Galina, Goldwurm, Stefano, Smith, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
Soggetti:
Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773276/
https://ncbi.nlm.nih.gov/pubmed/19744960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp430
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi