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An allergy-associated polymorphism in a novel regulatory element enhances IL13 expression
IL-13 is a central effector of Th2-mediated allergic inflammation and is critical for the induction of IgE synthesis. Common IL13 variants are associated with allergy phenotypes in populations of distinct ethnic background. We recently demonstrated that IL13 expression by human CD4(+) T cells is par...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773266/ https://ncbi.nlm.nih.gov/pubmed/19706623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp411 |
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