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The Peculiarities of Large Intron Splicing in Animals

In mammals a considerable 92% of genes contain introns, with hundreds and hundreds of these introns reaching the incredible size of over 50,000 nucleotides. These “large introns” must be spliced out of the pre-mRNA in a timely fashion, which involves bringing together distant 5′ and 3′ acceptor and...

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Bibliographic Details
Main Authors: Shepard, Samuel, McCreary, Mark, Fedorov, Alexei
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773006/
https://ncbi.nlm.nih.gov/pubmed/19924226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007853
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