Triptolide downregulates Rac1 and the JAK/STAT3 pathway and inhibits colitis-related colon cancer progression

Triptolide, a diterpenoid triepoxide from the traditional Chinese medicinal herb Tripterygium wilfordii Hook. f., is a potential treatment for autoimmune diseases as well a possible anti-tumor agent. It inhibits proliferation of coloretal cancer cells in vitro and in vivo. In this study, its ability...

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Bibliographic Details
Main Authors: Wang, Zhipeng, Jin, Haifeng, Xu, Ruodan, Mei, Qibing, Fan, Daiming
Format: Artigo
Language:Inglês
Published: Korean Society of Medical Biochemistry and Molecular Biology 2009
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772974/
https://ncbi.nlm.nih.gov/pubmed/19561401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2009.41.10.078
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