HIV-1 Vif-mediated ubiquitination/degradation of APOBEC3G involves four critical lysine residues in its C-terminal domain

During coevolution with the host, HIV-1 developed the ability to hijack the cellular ubiquitin/proteasome degradation pathway to counteract the antiviral activity of APOBEC3G (A3G), a host cytidine deaminase that can block HIV-1 replication. Abrogation of A3G function involves the HIV-1 Vif protein,...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Iwatani, Yasumasa, Chan, Denise S. B., Liu, Lin, Yoshii, Hiroaki, Shibata, Junko, Yamamoto, Naoki, Levin, Judith G., Gronenborn, Angela M., Sugiura, Wataru
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772817/
https://ncbi.nlm.nih.gov/pubmed/19887642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906652106
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires