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Ribose 2′-O Methylation of the Vesicular Stomatitis Virus mRNA Cap Precedes and Facilitates Subsequent Guanine-N-7 Methylation by the Large Polymerase Protein

During conventional mRNA cap formation, two separate methyltransferases sequentially modify the cap structure, first at the guanine-N-7 (G-N-7) position and subsequently at the ribose 2′-O position. For vesicular stomatitis virus (VSV), a prototype of the nonsegmented negative-strand RNA viruses, th...

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Xehetasun bibliografikoak
Egile Nagusiak: Rahmeh, Amal A., Li, Jianrong, Kranzusch, Philip J., Whelan, Sean P. J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772757/
https://ncbi.nlm.nih.gov/pubmed/19710136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01426-09
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