Human UPF1 Participates in Small RNA-Induced mRNA Downregulation

MicroRNAs (miRNAs) are endogenous antisense regulators that trigger endonucleolytic mRNA cleavage, translational repression, and/or mRNA decay. miRNA-mediated gene regulation is important for numerous biological pathways, yet the underlying mechanisms are still under rigorous investigation. Here we...

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Main Authors: Jin, Hua, Suh, Mi Ra, Han, Jinju, Yeom, Kyu-Hyeon, Lee, Yoontae, Heo, Inha, Ha, Minju, Hyun, Seogang, Kim, V. Narry
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772725/
https://ncbi.nlm.nih.gov/pubmed/19704008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00653-09
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